- S. M. Bader#, ..., M. Pellegrini# and M. Doerflinger#, “Non-apoptotic caspase-8 is critical for orchestrating exaggerated inflammation during severe SARS-CoV-2 infection” Nat. Comms., 2025. #Co-corresponding.
- S. M. Bader#, Calleja D#, Devine S# ..., D. Komander, “A novel PLpro inhibitor improves outcomes in a pre-clinical model of long COVID”, Nature Comms., 2025. #Shared first.
- S. M. Bader, ..., M. Pellegrini and M. Doerflinger, “IL-1 drives SARS-CoV-2 disease, independently of the inflammasome and pyroptotic signalling”, Cell Death Differ., 2025.
- J.P. Cooney, …, S.M. Bader, …, M. Pellegrini, “Combination antiretroviral therapy and MCL-1 inhibition mitigate HTLV-1 infection in vivo” Cell (accepted), 2025.
Publications
Selected work
This page is structured for public-facing publications and can be updated with complete citations, links, and preprints as needed.
- S. M. Bader, ..., M. Doerflinger, “Necroptosis does not drive disease pathogenesis in a mouse infective model of SARS-CoV-2 in vivo”, Cell Death Dis., 2024.
- S. M. Bader#, ..., M. Pellegrini, “SARS-CoV-2 mouse adaptation selects virulence mutations that cause TNF driven age-dependent severe disease with human correlates”, PNAS, 2023. #Shared first.
- A. John#, S. M. Bader#, ..., E. D. Goddard-Borger, “Conservation, abundance, glycosylation profile, and localization of the TSP protein family in Cryptosporidium parvum”, JBC, 2023. #Shared lead authorship.
- S. M. Bader, ..., A. L. Samson, “Endothelial Caspase-8 prevents fatal necroptotic hemorrhage caused by commensal bacteria”, Cell Death Differ., 2022.
- S. M. Bader, ..., M. Doerflinger, “Programmed cell death: the pathways to severe COVID-19?”, Biochem J., 2022.
- S. P Preston, ..., S. M. Bader, ..., Marc Pellegrini, “A necroptosis-independent function of RIPK3 promotes immune dysfunction and prevents control of chronic LCMV infection”, Cell Death Dis., 2022.
- S. P Preston, ..., S. M. Bader, ..., Marc Pellegrini, “Epigenetic Silencing of RIPK3 in Hepatocytes Prevents MLKL-mediated Necroptosis from Contributing to Liver Pathologies”, Gastroenterology, 2022.
- S. Seizova, ..., S. M. Bader, ..., C. J. Tonkin, “Transcriptional modification of host cells harbouring Toxoplasma gondii bradyzoites prevents IFN gamma-mediated cell death”, Cell Host Microbe, 2022.
- Renz, A., … S. M. Bader, … Michael Schindler and Christoph Kaleta. “Metabolic Modeling Elucidates Phenformin and Atpenin A5 as Broad-Spectrum Antiviral Drugs”, Preprints, 2022.
- M. D. Stutz, ..., S. M. Bader, ..., M. Pellegrini, “Macrophage and neutrophil death programs differentially confer resistance to tuberculosis”, Immunity, 2021.
- A. D. Uboldi, M.L. Wilde, S. M. Bader, and C.J. Tonkin, “Environmental Sensing and Regulation of Motility in Toxoplasma”, Mol. Microbiol., 2021.
- M. Doerflinger, ..., S. M. Bader, ..., M. J. Herold, “Flexible usage and interconnectivity of diverse cell death pathways protect against intracellular infection,” Immunity, 2020.