Stefanie M. Bader#, Lena Scherer, Reet Bhandari, Allan J. Motyer, James P. Cooney, Liana Mackiewicz, Merle Dayton, Dylan Sheerin, David V. L. Romero, Jan Schaefer, Jiyi Pang, Siqi Chen, Kael Schoffer, Le Wang, Xinyi Jin, Daniel Batey, Raymond K. H. Yip, Ishrat Zaman, Pradeep Rajasekhar, Matthew J. Gartner, Stephen Wilcox, Lachlan Whitehead, Smitha Rose Georgy, Ana Maluenda, Kathryn C. Davidson, Cody C. Allison, Rory Bowden, Kerstin Brinkmann, Marie-Liesse Asselin-Labat, Belinda Phipson, Maria C. Tanzer, Marco J. Herold, Andre L. Samson, James E. Vince, Andreas Strasser, Marc Pellegrini#, and Marcel Doerflinger#. “Non-apoptotic caspase-8 is critical for orchestrating exaggerated inflammation during severe SARS-CoV-2 infection.” Nature Communications 16, no. 1 (2025): 9822. #Co-corresponding.
DOIPublications
Selected work
Publications are listed in reverse chronological order. Where exact, public citation metadata was readily verifiable, the entries below have been expanded to full citations.
Stefanie M. Bader#, Dale J. Calleja#, Shane M. Devine#, Nathan W. Kuchel, Bernadine G. C. Lu, Xinyu Wu, Richard W. Birkinshaw, Reet Bhandari, Katie Loi, Rohan Volpe, Yelena Khakham, Amanda E. Au, Timothy R. Blackmore, Liana Mackiewicz, Merle Dayton, Jan Schaefer, Lena Scherer, Angus T. Stock, James P. Cooney, Kael Schoffer, Ana Maluenda, Elizabeth A. Kleeman, Kathryn C. Davidson, Cody C. Allison, Gregor Ebert, Gong Chen, Kasiram Katneni, Theresa A. Klemm, Ueli Nachbur, Smitha Rose Georgy, Peter E. Czabotar, Anthony J. Hannan, Tracy L. Putoczki, Maria Tanzer, Marc Pellegrini, Bernhard C. Lechtenberg, Susan A. Charman, Melissa J. Call, Jeffrey P. Mitchell, Kym N. Lowes, Guillaume Lessene, Marcel Doerflinger, and David Komander. “A novel PLpro inhibitor improves outcomes in a pre-clinical model of long COVID.” Nature Communications 16, no. 1 (2025): 2900. #Shared first authorship.
DOIS. M. Bader, ..., M. Pellegrini and M. Doerflinger, “IL-1 drives SARS-CoV-2 disease, independently of the inflammasome and pyroptotic signalling”, Cell Death Differ., 2025.
James P. Cooney, Ashley Hirons, Natasha Jansz, Cody C. Allison, Peter Hickey, Charis E. Teh, Tania Tan, Laura F. Dagley, Jumana Yousef, David Yurick, Georges Khoury, Simon P. Preston, Philip Arandjelovic, Kathryn C. Davidson, Lewis J. Williams, Stefanie M. Bader, Le Wang, Reet Bhandari, Liana Mackiewicz, Merle Dayton, William Clow, Geoffrey J. Faulkner, Daniel H. Gray, Lloyd Einsiedel, Damian F. J. Purcell, Marcel Doerflinger, and Marc Pellegrini. “Combination antiretroviral therapy and MCL-1 inhibition mitigate HTLV-1 infection in vivo.” Cell 188, no. 18 (2025): 4896-4912.e19.
DOIStefanie M. Bader, James P. Cooney, Reet Bhandari, Liana Mackiewicz, Merle Dayton, Dylan Sheerin, Smitha Rose Georgy, James M. Murphy, Kathryn C. Davidson, Cody C. Allison, Marc Pellegrini, and Marcel Doerflinger. “Necroptosis does not drive disease pathogenesis in a mouse infective model of SARS-CoV-2 in vivo.” Cell Death & Disease 15, no. 1 (2024): 100.
DOIStefanie M. Bader#, James P. Cooney#, Dylan Sheerin, George Taiaroa, Leigh Harty, Kathryn C. Davidson, Liana Mackiewicz, Merle Dayton, Stephen Wilcox, Lachlan Whitehead, Kelly L. Rogers, Smitha Rose Georgy, Anna K. Coussens, Samantha L. Grimley, Vincent Corbin, Miranda Pitt, Lachlan Coin, Raelene Pickering, Merlin Thomas, Cody C. Allison, Julie McAuley, Damian F. J. Purcell, Marcel Doerflinger, and Marc Pellegrini. “SARS-CoV-2 mouse adaptation selects virulence mutations that cause TNF-driven age-dependent severe disease with human correlates.” Proceedings of the National Academy of Sciences 120, no. 32 (2023): e2301689120. #Shared first authorship.
DOIAlan John#, Stefanie M. Bader#, Niccolay Madiedo Soler, Kharizta Wiradiputri, Swapnil Tichkule, Sean T. Smyth, Stuart A. Ralph, Aaron R. Jex, Nichollas E. Scott, Christopher J. Tonkin, and Ethan D. Goddard-Borger. “Conservation, abundance, glycosylation profile, and localization of the TSP protein family in Cryptosporidium parvum.” Journal of Biological Chemistry 299, no. 3 (2023): 103006. #Shared lead authorship.
DOIStefanie M. Bader, Simon P. Preston, Katie Saliba, Adam Lipszyc, Zoe L. Grant, Liana Mackiewicz, Andrew Baldi, Anne Hempel, Michelle P. Clark, Thanushi Peiris, William Clow, Jan Bjelic, Michael D. Stutz, Philip Arandjelovic, Jack Teale, Fashuo Du, Leigh Coultas, James M. Murphy, Cody C. Allison, Marc Pellegrini, and Andre L. Samson. “Endothelial Caspase-8 prevents fatal necroptotic hemorrhage caused by commensal bacteria.” Cell Death & Differentiation 30, no. 1 (2023): 27-36.
DOIStefanie M. Bader, James P. Cooney, Marc Pellegrini, and Marcel Doerflinger. “Programmed cell death: the pathways to severe COVID-19?” Biochemical Journal 479, no. 5 (2022): 609-628.
DOISimon P. Preston, Cody C. Allison, Jan Schaefer, William Clow, Stefanie M. Bader, Sophie Collard, Wasan O. Forsyth, Michelle P. Clark, Alexandra L. Garnham, Connie S. N. Li-Wai-Suen, Thanushi Peiris, Jack Teale, Liana Mackiewicz, Sophia Davidson, Marcel Doerflinger, and Marc Pellegrini. “A necroptosis-independent function of RIPK3 promotes immune dysfunction and prevents control of chronic LCMV infection.” Cell Death & Disease 14, no. 2 (2023): 123.
DOISimon P. Preston, Michael D. Stutz, Cody C. Allison, Ueli Nachbur, Quentin Gouil, Bang Manh Tran, Valerie Duvivier, Philip Arandjelovic, James P. Cooney, Liana Mackiewicz, Yanxiang Meng, Jan Schaefer, Stefanie M. Bader, Hongke Peng, Zina Valaydon, Pravin Rajasekaran, Charlie Jennison, Sash Lopaticki, Ann Farrell, Marno Ryan, Jess Howell, Catherine Croagh, Denuja Karunakaran, Carole Schuster-Klein, James M. Murphy, Theodora Fifis, Christopher Christophi, Elizabeth Vincan, Marnie E. Blewitt, Alexander Thompson, Justin A. Boddey, Marcel Doerflinger, and Marc Pellegrini. “Epigenetic Silencing of RIPK3 in Hepatocytes Prevents MLKL-mediated Necroptosis From Contributing to Liver Pathologies.” Gastroenterology 163, no. 6 (2022): 1643-1657.e14.
DOISimona Seizova, Ushma Ruparel, Alexandra L. Garnham, Stefanie M. Bader, Alessandro D. Uboldi, Michael J. Coffey, Lachlan W. Whitehead, Kelly L. Rogers, and Christopher J. Tonkin. “Transcriptional modification of host cells harboring Toxoplasma gondii bradyzoites prevents IFN gamma-mediated cell death.” Cell Host & Microbe 30, no. 2 (2022): 232-247.e6.
DOIRenz, A., … S. M. Bader, … Michael Schindler and Christoph Kaleta. “Metabolic Modeling Elucidates Phenformin and Atpenin A5 as Broad-Spectrum Antiviral Drugs”, Preprints, 2022.
Michael Dominic Stutz, Cody Charles Allison, Samar Ojaimi, Simon Peter Preston, Marcel Doerflinger, Philip Arandjelovic, Lachlan Whitehead, Stefanie M. Bader, Daniel Batey, Marie-Liesse Asselin-Labat, Marco J. Herold, Andreas Strasser, Nicholas P. West, and Marc Pellegrini. “Macrophage and neutrophil death programs differentially confer resistance to tuberculosis.” Immunity 54, no. 8 (2021): 1758-1771.e7.
DOIAlessandro D. Uboldi, Mary-Louise Wilde, Stefanie M. Bader, and Christopher J. Tonkin. “Environmental sensing and regulation of motility in Toxoplasma.” Molecular Microbiology 115, no. 5 (2021): 916-929.
DOIMarcel Doerflinger, Yexuan Deng, Paul Whitney, Ranja Salvamoser, Sven Engel, Andrew J. Kueh, Lin Tai, Annabell Bachem, Elise Gressier, Niall D. Geoghegan, Stephen Wilcox, Kelly L. Rogers, Alexandra L. Garnham, Michael A. Dengler, Stefanie M. Bader, Gregor Ebert, Jaclyn S. Pearson, Dominic De Nardo, Nancy Wang, Chenying Yang, Milton Pereira, Clare E. Bryant, Richard A. Strugnell, James E. Vince, Marc Pellegrini, Andreas Strasser, Sammy Bedoui, and Marco J. Herold. “Flexible Usage and Interconnectivity of Diverse Cell Death Pathways Protect against Intracellular Infection.” Immunity 53, no. 3 (2020): 533-547.e7.
DOI