Bader Lab

Infection, innate immunity, and the mechanisms of long-term disease

The Bader Lab investigates how infection drives tissue injury, inflammatory responses, and long-term disease consequences. We combine mechanistic biology with disease-relevant models, computational analysis, and AI-enabled research systems to understand how innate immune pathways shape host responses in infection and beyond.

Research focus

Immune sensing, inflammatory tissue injury, and persistent consequences of infection.

Approach

Mechanistic biology paired with translational thinking, computational analysis, and disease-relevant experimental systems.

Base

Center for Integrative Infectious Disease Research (CIID), Heidelberg.

AI tools & scientific systems

Building research infrastructure alongside the science

Alongside infection and post-viral disease research, the lab develops internal AI-enabled tools for scientific operations, structured knowledge work, and workflow design.

AI collaborator for scientific operations

A self-hosted lab AI supports drafting, planning, documentation, and internal infrastructure work across day-to-day scientific operations.

Structured methods intelligence

We are building source-linked literature and methods workflows that make research synthesis, comparison, and reuse more structured and inspectable.

Research memory and workflow design

The goal is not generic automation, but reliable systems that help preserve context, reduce friction, and keep scientific work moving.

Data infrastructure

Experimental database

The lab also maintains a private database environment for structured experimental records and collaborator-facing data exploration.

Private experimental database

A collaborator-facing database for experimental and translational research records, including structured mouse-study, histology, and omics views.

Access model

The database is not publicly open, but access may be granted to collaborators on request where sharing is appropriate.

Public overview

Read more about the database, what it contains, and how collaborator access works.

Support

Funding acknowledgement

We gratefully acknowledge support from CHS Stiftung and the National Health and Medical Research Council (NHMRC).